Hormones and Hair Loss: Why DHT is the Main Culprit.

Hormonal imbalances, specifically Androgenetic Alopecia, remain the primary driver of hair thinning for both men and women globally.

What is Androgenetic Alopecia?

The most common causes of hair loss in both male and female are hormone-related. Hormonal hair loss or “androgenetic alopecia,” is the most common cause of adult hair loss...

The Biological Mechanism: Testosterone vs. DHT

• The Role of Androgens

Male hormones (androgens) are believed to underline the mechanism of hair loss. Two key androgens involved are Testosterone and Dihydrotestosterone (DHT).

• How DHT Shrinks Hair Follicles

Testosterone is converted by the enzyme 5-alpha reductase to its active form DHT... Androgen receptor activation causes miniaturisation and eventual loss of hair.

• Disruption of the Growth Cycle (Anaphase)

Additionally, the growing phase (anaphase) of the hair cycle is also reduced, further contributing to hair loss.